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Study design This nationwide cohort study used Danish health registries

In the STEP trials (semaglutide) and SURMOUNT trials (tirzepatide) for obesity, participants with baseline binge eating behaviors showed improvements in eating-related measures alongside weight loss, as assessed by questionnaires such as the Control of Eating Questionnaire

The research community studying dual agonism has documented mean body weight reductions in the 20-22% range a roughly 35-50% improvement over the single-receptor benchmark

Measuring obesity is difficult

This interview has been lightly edited and condensed for clarity and length