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Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion

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The Journal of the American Osteopathic Association 2011;111:eS1520 Shuey MM, Lee KM, Keaton J, Khankari NK, Breeyear JH, Walker VM, Miller DR, Heberer KR, Reaven PD, Clarke SL, Lee J, Lynch JA, Vujkovic M, Edwards TL

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Furthermore, retatrutide has been shown to improve lipid profiles, with reductions in total cholesterol, LDL cholesterol, and triglyceride levels