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For example, patients with a BMI just below 27 but with significant metabolic dysfunction may still benefit from GLP-1 treatment, though prescribing in these cases is considered off-label and requires additional clinical justification

Compounded medications are prescribed based on a licensed provider's medical judgment, following a consultation and review of the patient's medical history

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You can start on your own and involve your doctor later if needed

Inspired by rat amylin, which is less prone to dimerize, the enhanced stability of pramlintide compared to human amylin was achieved by introducing three amino acid substitutions (pro25,28,29) into the sequence of human amylin ( Table 1 )