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Studies of bariatric surgery consistently demonstrate bone density decreases following major weight loss, and similar patterns may occur with pharmacologically induced weight reduction

Prescribers should refer to the full prescribing information for these agents when making prescribing decisions

J Cancer Prev 2018;23:183-90.ArticlePubMedPMC 22

Among the 4 brand-name products with paragraph IV submissions, the median time from brand-name approval to first paragraph IV challenge was 6.8 years (IQR: 6.0-7.4)
