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Who Are the Ideal Candidates

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Source: Evaluate Pharma, World Obesity Federation, Putnam Analysis Q2, 2025 Unmet Needs and Potential Differentiation Levers Despite extraordinary promise, there are still unmet needs that biopharma companies can target to address: GI Tolerability The most common GI adverse events (nausea, vomiting, and diarrhea) often lead to therapy discontinuation

Understanding the fatigue that can accompany GLP-1 treatment also requires blood work context, since deficiency-driven fatigue looks different from adjustment-phase fatigue

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