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As the field increasingly embraces combination therapies and network-level interventions, revisiting these systems with modern tools may yield treatments that address not only caloric intake but also the behavioral and psychological dimensions of metabolic disease

Think about what you need to do in the long and short term

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In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

They then evaluated the repeatability of the study findings among type 2 diabetes patients from different periods