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Sorli C, Harashima SI, Tsoukas GM, Unger J, Karsbol JD, Hansen T, Bain SC (2017) Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial

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These are off-label approaches and should only be pursued under direct medical supervision

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When oxidative throughput approaches or exceeds regenerative redox-buffering capacity under constrained substrate inflow, a rate-limiting metabolic state can be conceptualizedreferred to here as a redox bottleneck as discussed in Sect