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Among the mechanisms, our research group and others have demonstrated that the gut microbiota fermentation (i.e., bacterial digestion of specific compounds) of specific prebiotics or other non-digestible carbohydrates is associated with the secretion of enteroendocrine peptides, such as the glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), produced by L-cells

The results of an independent study led by Mayo Clinic has found that the MyPhenome Hungry Gut test (Phenomix Sciences) can predict a patients response to semaglutide, thereby reducing variability in response to this weight loss medication.The study, Performance of a Machine-Learning Gene Risk Score Biomarker on Predicting Response to Semaglutide, enrolled 84 participants with obesity (BMI 38.86.9 kg/m2) who were prescribed semaglutide

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