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Description
however, a new paradigm for HFpEF development proposes that a systemic proinflammatory state, induced by comorbidities, is responsible for these myocardial structural and functional changes [11]

Potential Cardiometabolic Benefits: By supporting weight loss and glycemic control, it may also help reduce risk factors associated with metabolic syndrome
Digital rectal examination (DRE) 2

Well-Tolerated It is generally well-tolerated, with common side effects, including nausea and diarrhea, which often subside over time
The oral versions of semaglutide introduce a different set of hurdles
