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Longer diabetes duration correlated with older age, a higher proportion of females, a history of stroke, peripheral arterial disease, insulin use, and poorer kidney function

This pattern is well documented and is one reason providers often recommend adjusting meal timing and sleep position alongside dose changes rather than waiting for symptoms to resolve on their own

In that context, a 16% benefit is a big deal. He notes that these findings were among patients at high risk for a cardiovascular event and may not apply to lower-risk populations

This effect can be particularly beneficial for patients who seek to manage their weight effectively and sustainably

While less convenient for self-injection, its still a viable option, especially with help