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This approach addresses the fact that BMI in the exposed group is potentially already affected by GLP-1 RA

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Developing Products for Weight Management Revision 1

Disrupted sleep raises cortisol and ghrelin (the hunger hormone) while suppressing leptin (the satiety hormone)

Priority medicines include: GLP-1 receptor agonists such as semaglutide dual GIP/GLP-1 agonists such as tirzepatide future triple-receptor agonists SGLT2 inhibitors for heart and kidney protection medicines targeting liver fat, inflammation and insulin resistance Trials must examine long-term safety, muscle preservation, affordability and what happens after treatment stops