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RAF Scores: HCC 18 0.302 HCC 19 0.105 MEAT Criteria Element Example Monitor Blood glucose levels, A1C, weight, foot exam, eye exam Evaluate Review of A1C results, renal function, or symptoms Assess Type 2 DM uncontrolled with A1C 8.9%, worsening neuropathy Treat Prescribed Metformin, adjusted insulin dose, dietary counseling TAMPER Criteria Component Example T Treatment Oral hypoglycemics, insulin therapy A Assessment A1C 8.9%, not at goal M Monitor Follow-up labs, blood sugar log P Plan Recheck A1C in 3 months

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In SURMOUNT-5, once weekly tirzepatide at the maximum tolerated dose (MTD 10 mg or 15 mg) compared with semaglutide (MTD 1.7 mg or 2.4 mg) resulted in significantly greater body weight reduction in adults living with obesity without T2D