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Surprisingly, an initial eGFR dip of over 10% after initiating SGLT2i did not have any impact on the subsequent cardiovascular death, hospitalization for heart failure, and incident or worsening kidney disease and demonstrated beneficial effects in people with heart failure and reduced ejection fraction (Kraus et al., 2021

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Together, these effects could amplify weight loss, offering better results than using either medication alone

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Oral Wegovy Side Effects and Safety Common side effects of oral Wegovy include nausea, diarrhea, reduced appetite, and stomach discomfort, primarily during the initial phase