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Description
Muscle and Fat (Insulin Sensitivity): GLP-1 RAs enhance glucose uptake in muscle and adipose tissue via the PI3K/Akt pathway, improving overall insulin sensitivity (Zheng et al., 2024)
Experiments using patches of plasma membrane from human -cells or rat insulinoma cell lines (INS-1) demonstrated that an Epac-selective cAMP analogue significantly reduced the concentration of ATP necessary for 50% inhibition of K + ATP channels [75]
doi: 10.1016/S0140-6736(20)32205-4 5 LiuXYZhangNZhangSXXuP
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