fda approved glp-1 agonists Glucagon-like peptide 1 receptor (GLP-1 RAs) administered at off-label reduced dosing maintained weight-loss benefits, with patients retaining the effects even with 2-4 weeks between doses. http://ms.spr.ly/6188SW4Iw Comparing GLP-type therapies for weight
Description
SCREEN FOR COMORBIDITIES Metabolic disturbances Given the high prevalence of metabolic disturbances in PCOS, screening for glucose and lipid abnormalities should be performed regardless of body mass index
Switching between GLP-1 medications does happen in clinical practice, usually when a patient has reached a plateau, experienced intolerable side effects, or when insurance coverage changes
Dual GLP- 1 Receptor AgonistsCagriSema A long-acting amylin analog called cagrilintide is being developed in conjunction with semaglutide 2.4 mg (CagriSema) to treat T2DM [101]

The dual activation appears to create additive benefits

C.AtkinS
