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Temporary side effects like nausea are generally manageable and dont signal permanent harm

At the same time, improved ovulatory function during treatment may increase the risk of unintended conception if contraception is inconsistent

Furthermore, it has long been theorized that cancer cells exhibit heightened glucose uptake and rely on glucose as a primary fuel for proliferation because it is a substrate cancer cells use as an energy source in aerobic glycolysis, resulting in tumor progression [27]

In addition, this report is a consensus of expert endocrinologists representing South Asian countries including India, Pakistan, Bangladesh, Nepal, Sri Lanka, Afghanistan and the Maldives on essential recommendations related to the use of GLP-1 RAs in a real-world scenario

The 39 amino acid sequence of tirzepatide shares similarity with that of GIP, GLP-1 and exendin-4 and is characterized by an acyl chain attached to the lysine residue at position 20 contributing to albumin binding and half-life extension to 5 days [41]