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Originally developed for type 2 diabetes, these injectable drugs mimic a natural hormone called glucagon-like peptide-1 (GLP1-1) that regulates appetite and blood sugar

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The Result: You feel physically full for a longer duration after eating, which naturally reduces the frequency of food intake

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As primary substrates for DPP-IV are GLP-1, GLP-2, and gastro-insulinotropic peptide (GIP), DPP-IV gene-deficient mice show improved postprandial glucose control and are resistant to progression of obesity and hyperinsulinemia (Drucker 2002