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These include loss of muscle mass, nutrient deficiencies, metabolic dysfunction, digestive discomfort, and nausea

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been pivotal for obesity treatment, achieving 1525 % weight loss over 1224 months, but questions remain about the potential influence of concomitant losses in muscle mass

and (iii) to balance the actual warning with the opportunity for future discovery about their benefits.

Upper respiratory tract infections (URTIs) were the most frequently reported adverse event (8 of 12 reporting studies, 66.7%), occurring at rates comparable to controls across RCTs (GRADE: MODERATE certainty)