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The plateau is not medication failure

The future could also bring more diversification in treatments, as many new drugs are in development that could yield new ways to manage weight loss long-term, provide better safety profiles, and combine drugs that target several different appetite-modifying hormones

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In the STEP 1 trial, once weekly GLP-1 agonist at 2.4 mg with lifestyle intervention led to a mean body weight reduction of 14.9 percent at 68 weeks, compared with 2.4 percent with placebo 2