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Food-related social activities became less centered on eating itself, with participants noting ability to socialize without excessive food consumption

Some researchers believe that GIP receptor activation partially offsets the nausea caused by GLP-1 stimulation, which could explain why some patients tolerate tirzepatide better than pure GLP-1 agonists despite receiving more potent appetite suppression

Tirzepatide underwent extensive clinical trials, demonstrating significant benefits for individuals with type 2 diabetes and obesity

In a phase 2b trial, 392 patients with bridging fibrosis or compensated cirrhosis (F3-F4) were randomized to receive placebo, selonsertib 18 mg, cilofexor 30 mg, or firsocostat 20 mg, alone or in two-drug combinations, once daily, for 48 weeks

However, it cannot be ruled out that the improvements in plaque psoriasis highlighted in this case report may be due to other factors as well as sun exposure