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In the interim, policies that reduce barriers to FDA-approved medications for alcohol and opioid use disorder will benefit public health

Therefore, additional preclinical research is necessary to assess the feasibility of targeting vagal innervation at the branch level, such as the hepatic, cardiac, and bronchial branches of the vagus nerve

Orlistat, phentermine/topiramate, naltrexone/bupropion, and the incretin-based drugs liraglutide and semaglutide, both GLP-1 receptor agonists (GLP-1RA), and tirzepatide, a biased dual GIP/GLP-1 receptor agonist, are currently both FDA and EMA approved for the management of non-syndromic obesity 10

and those with lower incomes
