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As a dietary supplement, creatine monohydrate is widely used to enhance athletic performance, increase muscle mass, and improve exercise capacity

The primary B12 risk is indirect: marked appetite suppression may reduce consumption of animal-derived foods, the main dietary source of B12

These comparisons point out that tirzepatide offers benefits from targeting two hormones

No patient developed lactic acidosis during a follow up period of 26.8 months.37 Although these studies did not report the glycemic effects, it is likely that better glycemic control was a contributor to reduced morbidity and mortality
Depression and mood alterations warrant particular attention, especially in individuals with a history of mood disorders