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Journal of Clinical Pharmacology , 64(1), 65-72

PlexusDx offers multiple GLP-1 options including oral semaglutide, compounded tirzepatide, and dual-compound formulations like GLP-Squared, all sourced from licensed 503A compounding pharmacies

95% CI, 0.8-0.99) for those who received GLP-1 receptor agonists

Now, when the shortage stops or the shortage is lifted by the FDA, we will no longer be able to make a compounded form of semaglutide or tirzepatide for patient use. However, Binkleys Health & Wellness Compounding Pharmacy in Midtown is working on a semaglutide formulation with additives that it will be allowed to continue dispersing even once the shortage ends

Additional safety considerations include tirzepatide's boxed warning for thyroid C-cell tumors, risk of pancreatitis (symptoms include severe persistent abdominal pain, sometimes radiating to the back), gallbladder disease, and potential complications in patients with diabetic retinopathy