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Up to 25% of weight loss from GLP-1 medications alone is lean mass , including muscle

The differences lie in manufacturing oversight (Ozempic is FDA-approved, Strive is compounded), delivery method (Ozempic uses pre-filled pens, Strive uses multi-dose vials), formulation additions (Strive may include glycine, B12, or B6), and cost (Ozempic costs $800 to $1,200 per month without insurance versus $90 to $200 per month for Strive)

"Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain"

Zobel et al., 2021), hyperglycaemia (Mapanga and Essop, 2016), increased endothelial production of reactive oxygen species (ROS) (Ceriello et al., 2011