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Among the mechanisms, our research group and others have demonstrated that the gut microbiota fermentation (i.e., bacterial digestion of specific compounds) of specific prebiotics or other non-digestible carbohydrates is associated with the secretion of enteroendocrine peptides, such as the glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), produced by L-cells

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In China, over 60 late-stage drugs are undergoing clinical trials, and may compete with those from incumbents Novo Nordisk and Eli Lilly.

GLP-1 receptor agonists can influence cardiovascular markers, including blood pressure

There was a dose-related decrease in disease activity from baseline to 24-weeks for patients on ianalumab compared to placebo