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These drugs mimic the hormone glucagon-like peptide-1, which boosts insulin production, slows digestion and regulates appetite, helping to lower blood sugar and support weight management

The rebound in body weight is related to increased food intake, lipid metabolism (Zhong et al., 2022), the persistent presence of immune cell phenotypes in adipose tissue (van Baak and Mariman, 2023) and adipocyte stress (Van Baak and Mariman, 2019)

Scientists identified multiple physiological mechanisms through which this effect can be achieved

Kenneth Hopkins