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Back Blume, N, Skouv, J, Larson, L-I, et al (Nov 1995) 'Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis', Journal of Clinical Investigations , 96, 2227-35

[DOI] [PubMed] [Google Scholar] 103.Wei L., Mo W., Lan S., Yang H., Huang Z., Liang X., Li L., Xian J., Xie X., Qin Y., et al

Just two weeks later, on 1 April 2026, the FDA approved Foundayo, Eli Lillys brand name for orforglipron, making it the first small-molecule, non-peptide oral GLP-1 receptor agonist approved for chronic weight management

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Kidney Issues: There have been reports of acute kidney injury (AKI), particularly in patients who are dehydrated