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2.4% with placebo, when used with diet and exercise

Tirzepatide has shown significant benefits for weight loss and diabetes control, making it a promising option for those struggling with these conditions

The figure below captures this central tension: payers are almost evenly split in their perspectives on treatment of obesity, with some regarding pharmaceutical coverage for obesity as a response to a chronic medical condition, while others see it more as addressing a lifestyle issue

Studies have suggested that in addition to diabetes, GLP-1R agonists may also have a beneficial effect on many other diseases such as cardiovascular disease, central nervous disorder, and tumors (2123)

- The distinction between alpha- and beta-cells was not clear due to variability in staining intensity [163]