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My reward system was recalibrating to respond to sunlight and laughter and the smell of lavender instead of requiring the sledgehammer of engineered food
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A median split of the GLP-1 group based on average daily physical activity (9.7 min/day) revealed a trend, suggesting that higher physical activity participation was associated with an attenuation of the increase in RHR observed with GLP-1 RA therapy ( P = 0.09

Genetic variations in GLP-1 receptor sensitivity, glucose metabolism, and gut microbiome composition influence how aggressively the GLP-1 pathway responds, and therefore how pronounced initial gastrointestinal effects are
