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The present invention also provides a solid phase peptide process for the preparation of Fmoc- Gln(Trt)-Ala-Ala-Lys(C18 diacid mono-t -butyl -y-Glu(AEEA-AEEA)-OtBu)-Glu(OtBu)-Phe- Ile-Ala-Trp (Boc)-OFl of fragment-4 which comprises: a) anchoring Fmoc-Trp(Boc)-OFl to a resin in presence of a coupling agent

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