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The introduction of GLP-1s for weight loss has been a dysfunctional mess, thanks to pharmaceutical companies, insurance plans, pharmacy chains, and the federal government.

A new blockbuster class of therapeutics, glucagon-like peptide 1 (GLP-1) analogs (eg, semaglutide), shows promise at curbing both diseases

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In vitro, the protein levels of IL-1 and TNF- in lipopolysaccharide-stimulated BV-2 microglia were also decreased by liraglutide