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Variants in GLP1R (the GLP-1 receptor itself), GIPR (rs1800437 is the headline variant for differential GLP-1 response), FTO (appetite regulation), MC4R (satiety signaling), and TCF7L2 (insulin response) are associated with measurably different response patterns to semaglutide and tirzepatide

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Here, we will provide an overview of the existing literature around diabetes and metabolism in the context of cancer and cachexia

GLP-1 (Glucagon-Like Peptide-1) receptor agonists are game-changing medications that: Suppress appetite, making it easier to control portion sizes

While patients are usually born at a normal weight, genetic differences affecting hunger regulation, satiety, and metabolism can lead to rapid weight gain