glp-1 receptor agonists and cardiovascular outcome trials an update Kidney Outcomes Among Patients With CKD Receiving Agonists: A Systematic Review and Meta-Analysis of Randomized Glucagon-like peptide 1 receptor agonists:
Description
Efficacy studies have demonstrated this additive effect with metformin, sulfonylureas, and thiazolidinediones given in combination with saxagliptin and linagliptin

Weight loss drugs like GLP-1s mimic the action of this natural hormone
A.HolmJ

[1] [4] The timeline for GLP-1 medications to "kick in" varies depending on which therapeutic effect you're measuring and the specific medication used
As such, it is not surprising when unintended consequences of chronic receptor activation emerge
