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Gradual dose escalation according to the prescribed titration schedule allows the body to adapt progressively to the medication

Semaglutide works by mimicking GLP-1 (glucagon-like peptide-1), a naturally occurring hormone involved in hunger signaling, digestion, and insulin response

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Avoid heat, direct sunlight, glove compartments, and checked luggage delays that could expose the medicine to uncontrolled temperatures

Front Endocrinol (Lausanne) 12:645507 Ahrn B, Atkin SL, Charpentier G et al (2018) Semaglutide induces weight loss in subjects with type 2 diabetes regardless of baseline BMI or Gastrointestinal adverse events in the SUSTAIN 1 to 5 trials