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This resulted in the first generation of GLP-1 receptor agonists, including exenatide and lixisenatide

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Additionally, Semaglutide reduces oxidative stress by decreasing the production of reactive oxygen species (ROS) and increasing the activity of antioxidant enzymes

Agus A, Planchais J, Sokol H
Insulin regulates POMC neuronal plasticity to control glucose metabolism
