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GLP-1 medications address biological factors like hunger cues and insulin function, but they dont eliminate the need for sustainable healthy habits

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DPP-4 regulates adipokines, as leptin and adiponectin, and a negative correlation between blood DPP-4 activity and circulating adiponectin levels in lean and obese subjects has been observed [48,49]

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We then estimated the treatment adherence effect using marginal structural models incorporating time varying covariates on the composite endpoint