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Pre-menstrually, when both oestrogen and histamine levels are elevated, this can manifest as dizziness, fatigue, headaches, irritability, and intense cravings for sugary foods as the body attempts to stabilise blood glucose symptoms that are frequently misattributed to PMS alone

Espinosa, A

Obesity is now considered a chronic disease that in some individuals requires treatment

Additional information This article is part of the Topical Collection on Therapeutic Trials Rights and permissions About this article Cite this article Goud, A., Zhong, J., Peters, M

In many cases, the most important changes involve nutrition, activity, side-effect management, and medical monitoring