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Description
Mutations in genes that play a major role in the central or peripheral control of energy balance identify rare hereditary obesity syndromes
Some myo-inositol is converted to DCI in the body
It also upregulates brain cortical autophagy and ameliorates apoptosis [63]
The FDA approval for Saxenda covers two patient populations: Adults BMI of 30 or higher (clinical obesity), regardless of other health conditions
Rational combinations with orthogonal metabolic agents can be explored, with careful endpoint alignment and safety monitoring
