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However, the rapid adoption occurs against a backdrop of worsening obesity and diabetes epidemics, with significant geographic and racial disparities requiring targeted interventions ^28

Another recent study found that Zoloft was associated with an average gain of nearly 0.5 pounds at 6 months

Coverage Cuts and Mid-Treatment Disruptions Major insurers like CVS Caremark and Aetna, along with state programs such as Medi-Cal, are reducing or removing coverage for key GLP-1 medications, including Wegovy and Zepbound

Subsequently, SUSTAIN-6 examined semaglutide (0.5 mg/week or 1.0 mg/week subcutaneous) across 3,297 participants [2]

Unlike current injectable GLP-1 therapies, Orforglipron is taken orally, opening new opportunities for patient compliance and accessibility
