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Sarah Oreck explained that the key takeaway from this study is that rapid weight loss can make it harder to recognize when an eating disorder is re-emerging, precisely because the changes are so often socially reinforced. Recovery and asking for help can be challenging -- seek out support groups and reach out to trusted professionals and friends or family

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Mice with PVN-selective deletion of GLP-1R (using Sim1 cre) have impaired stress-induced HPA axis activation, and this is further accompanied by protection from stress-induced weight loss, reduced stress-induced cardiovascular endpoints and reduced anxiety-like behavior [813]

10.1016/j.bioadv.2023.213467 [DOI] [PubMed] [Google Scholar] Turner J

Given the impact of androgen excess on multiple reproductive and metabolic parameters of females, such analyses are deemed mandatory in order to define the potential utility of such compounds for the personalized treatment of women suffering from PCOS