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Among the mechanisms, our research group and others have demonstrated that the gut microbiota fermentation (i.e., bacterial digestion of specific compounds) of specific prebiotics or other non-digestible carbohydrates is associated with the secretion of enteroendocrine peptides, such as the glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), produced by L-cells

GLP-1 receptor agonists can reduce thirst signals and increase fluid loss through gastrointestinal changes, making intentional hydration critical during treatment

in our licensed states

Tirzepatide is not currently approved or recommended for smoking cessation

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