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Weeks 5-8: 4 mg per week (80 units) The first escalation doubles the dose

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Insulin remains stable at up to 25C for 28 days after opening

For example, acute exposure to high glucose concentration increases GIP receptor expression in pancreatic -cells whereas chronic exposure to high glucose concentration reduces GIP receptor in -cells 19

Fat and protein stimulation of GIP amplifies the release of insulins counter-regulatory hormone, glucagon, which serves to keep blood sugar from dropping too low