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Since it targets two hormones (GLP-1 and GIP) instead of just one (like semaglutide), it can be more effective for weight loss and blood sugar control

Lilly presented full data from two retatrutide trials, one in treatment naive type 2 diabetes patients and another in patients with obesity, at the American Diabetes Association meeting in New Orleans

Semaglutide Breakdown: Indications and Mechanisms Semaglutide is a well-established GLP-1 receptor agonist that has become a foundational therapy in modern obesity and diabetes treatment

The net result is a compound that addresses energy expenditure from three distinct angles simultaneously a property no dual agonist can replicate

Injection site reactions: Some individuals may experience redness, swelling, or irritation at the site of the injection