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Table 10: Results at Week 26 in a Trial Comparing TRESIBA U-200 to Insulin Glargine U-100 in Adult Patients with Type 2 Diabetes Mellitus on OAD(s)* Study F: TRESIBA Administered at the Same Time Each Day in Insulin Nave Adult Patients as an Add-on to One or More of the Following Oral Agents: Metformin, Sulfonylurea, Glinides or Alpha-Glucosidase Inhibitors The efficacy of TRESIBA was evaluated in a 26-week randomized, open-label, multicenter trial in Asia in 435 insulin nave patients with type 2 diabetes mellitus inadequately controlled on one or more oral antidiabetic agents (OADs) at baseline

NCT04537637

-Mark R

2: Failure of the counter-regulatory response to weight loss According to the set-point theory, mammalian physiology has evolved to prevent body weight loss under variable environmental conditions [30]

This pattern reflects the medication's role as a tool that supports behavior change rather than a permanent fix