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2.4.2 Neuroendocrinereproductive axis: coupling of appetitive centers and reproductive neurons The expression of receptors in hypothalamic reproductive nuclei provides a biological basis for a direct influence on the reproductive axis

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Importantly, dual and triple GLP-1R/Gastric inhibitory polypeptide receptor (GIP-R) agonists have been developed, maximizing the beneficial effects and minimizing the adverse effects of these agents

while some brain cells sustain elevated cAMP levels when exposed to semaglutide, others experience only temporary spikes before dropping back to baseline