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Description
A plaques, which form and deposit in different regions of the brain, are recognized as foreign material by the brain and trigger an inflammatory and immune response by activating the microglia leading to neuronal degeneration and synaptic damage (2, 30)

When retatrutide continuously activates GLP-1 receptors on sensory neurons, those neurons can become "trained" to fire more easily, lowering the threshold for what triggers a sensory response

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[DOI] [PubMed] 33.Freitas S, Merkle HP, Gander B

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