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These may include medications with active ingredients such as semaglutide, tirzepatide, liraglutide, setmelanotide, phentermine, orlistat, and naltrexone-bupropion

The most common are digestive, such as nausea or a queasy stomach, and they tend to appear during dose increases and settle as your body adjusts

According to the researchers, their findings broadly suggest that small-molecule GLP-1s could have applications in dysregulating reward signaling, creating implications for the drugs treatment of substance-use disorder and binge-eating
