glp 1 gip agonist Dual GIP/GLP-1 receptor agonists: New advances for treating type-2 diabetes Major physiological roles of GLP-1

Peluso, 2021)

Owing to these effects, liraglutide, a GLP-1 analog, has been studied as a potential drug for the treatment of pre-eclampsia, a pregnancy specific disorder, defined as new-onset hypertension after 20th week of gestation accompanied by proteinuria, as it is found to have anti-inflammatory and antioxidative effects (89)

While some physicians are prescribing these medications for their approved uses of treating type 2 diabetes, obesity and obstructive sleep apnea, others are frequently making off-label prescriptions

Diabetes 7 , 441448 (2016) Mentlein, R., Gallwitz, B

Nonetheless, the effect of GLP-1 RAs on HR should not be overlooked, because studies have shown that an elevated HR was potentially associated with a higher cardiovascular risk [353637]