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Ideal Candidates Retatrutide may work best for adults with obesity, which is defined as a BMI of 30 kilograms per square meter or higher, or for those with a BMI over 27 kilograms per square meter who have obesity-related health issues such as type 2 diabetes, high blood pressure, or sleep apnea

Off-Label Prescribing: Many longevity treatments including metformin, rapamycin, low-dose naltrexone, and daily tadalafil are manufactured in FDA-registered facilities for specific approved conditions but are prescribed off-label within longevity-focused or age-related wellness discussions

The SURMOUNT-1 study was a placebo-controlled 72-week trial in obese subjects that randomized 2,539 participants without diabetes into four equally large study arms with placebo or one of the three tirzepatide doses (5, 10, or 15 mg once weekly)

There is currently no cure for RRP

Therefore, gradual titration and patient education are essential