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Description
Quesada I, Tudur E, Ripoll C, Nadal
a meaningful result, but one that will require replication in larger, longer trials before combination therapy of this kind becomes a standard clinical option
Why it matters: A larger research signal is not the same as a settled treatment option
Kristina S
The observed interactions between the ECD and ECL1/3 in the inactive GLP-1R structure presented here agree with previous studies suggesting that the ECD stabilized an inactive state of the glucagon receptor through interactions with ECL1 and ECL3 20
